What is the chemical effect of rotenone on aerobic metabolism?
A) The flow of electrons from NADH to CoQ is blocked.
B) The flow of electrons from cytochrome a,a3 to oxygen is blocked.
C) Oligomycin blocks the proton transfer through F0 of ATP synthase and therefore blocks the phosphorylation of ADP to form ATP.
D) The transport of ATP out of and ADP into the mitochondria is blocked.
E) Oxidative phosphorylation is uncoupled from electron transport and all the energy is lost as heat.
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