The anticancer drug cisplatin disrupts:
A) histone binding to DNA.
B) supercoiling of DNA.
C) chromatin-DNA binding.
D) replication and transcription.
E) None of the above.

Question

Quizplus · Accepted Answer

Cisplatin disrupts the process of replication and transcription by covalently binding to DNA and causing cross-linking of strands, leading to the inhibition of DNA synthesis and cell division. This ultimately results in cell death, making cisplatin a commonly used anticancer drug.

The Anticancer Drug Cisplatin Disrupts