Which amino acids in chymotrypsin are found in the active site and are participants in substrate cleavage?
A) his, ser, asp
B) his, ser
C) asp, lys
D) lys, arg
E) his, ser, arg

Question

Quizplus · Accepted Answer

The active site of chymotrypsin contains a catalytic triad consisting of histidine (His), serine (Ser), and aspartate (Asp). These amino acids play a crucial role in the mechanism of substrate cleavage, with Ser acting as a nucleophile, His as a base, and Asp stabilizing the charge.

Which Amino Acids in Chymotrypsin Are Found in the Active