Allosteric effectors:
A) can cause large changes in enzymatic activity.
B) can lead to a decrease in the availability of a protein.
C) do not alter the sensitivity of a metabolic pathway.
D) decrease the sensitivity of the enzyme at nearly all concentrations of substrate.
E) alter enzyme activity by binding to the active site of an enzyme.

Question

Quizplus · Accepted Answer

Allosteric effectors can cause large changes in enzymatic activity as they bind to specific sites on the enzyme, causing a conformational change that can activate or inhibit the enzyme's activity.

Answer: B
 This statement is incorrect. Allosteric effectors may affect the availability of a protein indirectly by regulating its activity, but they do not directly lead to a decrease in its availability.

Answer: C
 This statement is incorrect. Allosteric effectors can alter the sensitivity of a metabolic pathway by regulating the activity of enzymes within the pathway.

Answer: D
 This statement is incorrect. Allosteric effectors can increase or decrease the sensitivity of an enzyme depending on the specific effectors and their concentrations.

Answer: E
 This statement is incorrect. Allosteric effectors bind to specific sites on the enzyme other than the active site, causing a change in the enzyme's activity. They do not bind directly to the active site.

Allosteric Effectors