In research on aging (both cellular aging and organismal aging), it has been found that aged cells do not progress through the cell cycle as they had previously. Which of the following would provide evidence that this is related to cell signaling?

Question

Quizplus · Accepted Answer

The decreased affinity of growth factor receptors for their respective ligands suggests that there is a problem with the cell signaling. Growth factor signaling is crucial for cell cycle progression, and a decrease in receptor affinity would indicate a decrease in signaling efficiency, leading to impaired cell cycle progression. Decreased ATP production and hormone production, as well as decreased numbers of cytoplasmic ribosomes, are not directly related to cell signaling and would not provide evidence for this hypothesis.

In Research on Aging (Both Cellular Aging and Organismal Aging)