A genetic change that caused a certain Hox gene to be expressed along the tip of a vertebrate limb bud instead of farther back helped make possible the evolution of the tetrapod limb. This type of change is illustrative of ________.
A) the influence of environment on development
B) paedomorphosis
C) a change in a developmental gene or its regulation that altered the spatial organisation of body parts
D) heterochrony
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