A genetic change that caused a certain Hox gene to be expressed along the tip of a vertebrate limb bud instead of further back helped make possible the evolution of the tetrapod limb. This type of change is illustrative of

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This type of genetic change is a change in the spatial organisation of body parts, which is caused by a change in a development gene or its regulation. This is an example of a regulatory change in the Hox gene expression that led to the evolution of tetrapod limbs.

A Genetic Change That Caused a Certain Hox Gene to Be