Using St.John's wort may interfere with depression medications.

Question

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St. John's wort can decrease the effectiveness of depression medications, including selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs). It can also interact with other medications, such as birth control pills and blood thinners. Therefore, it is important to talk to a healthcare provider before using St. John's wort or any other supplements.

Using St.John's Wort May Interfere with Depression Medications