When Aplysia learns a simple, classically conditioned response, structural and functional changes in the three neurons involved create a memory circuit that eventually becomes established as a long-term memory.

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This statement is true. Aplysia is known for its ability to learn and remember simple, classically conditioned responses, and studies have shown that structural and functional changes in the neurons involved contribute to the establishment of long-term memory circuits.

When Aplysia Learns a Simple, Classically Conditioned Response, Structural and Functional