Consider a population of size N_e with a new mutation that confers a fitness advantage of 1 + s. This new allele will be more likely to go to fixation due to selection if A) N_e is large and s is large. B) N_e is small and s is large. C) N_e is large and s is small. D) N_e is small and s is small.

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In evolutionary biology, the probability of a new advantageous mutation going to fixation in a population is higher when both the population size and the selection coefficient (s) are large. A large population size reduces the impact of genetic drift, allowing selection to more effectively drive the advantageous allele to fixation. A large selection coefficient means the fitness advantage conferred by the mutation is significant, further increasing its chances of becoming fixed in the population.

Consider a Population of Size Ne with a New Mutation

Consider a Population of Size N_e with a New Mutation