The bond between the nitrogenous base and the sugar in a nucleoside is a glycosidic bond. Which type of reagent should cleave this bond?
A) acid
B) base
C) acid or base
D) neither acid nor base
E) It depends on which nitrogenous base and which sugar are present.

Question

Quizplus · Accepted Answer

A glycosidic bond involves a linkage between a sugar molecule and a nitrogenous base. Since this bond involves a sugar, it can be hydrolyzed by an acid. Therefore, an acid would be the best choice to cleave this type of bond.

The Bond Between the Nitrogenous Base and the Sugar in a Nucleoside