You are working in a lab where you are studying a disease that is known to be caused by a single nucleotide change, although the effect this change ultimately has on the protein's structure/function is unknown. You have DNA samples from multiple patients that you suspect of having this disease. What is the most efficient way to test the samples for the relevant mutation?

Question

Quizplus · Accepted Answer

DNA sequencing is the most direct and accurate way to identify the specific nucleotide change responsible for the disease. Other techniques like Western blotting, karyotyping, and amniocentesis may provide valuable information but are not specific to identifying a single nucleotide mutation.

You Are Working in a Lab Where You Are Studying