What is the rare situation called when only one of the two copies of a particular tumor-suppressor gene needs to be inactivated before there is a progression toward cancer?

Question

Quizplus · Accepted Answer

This situation is known as haploinsufficiency, where a single functional copy of a tumor-suppressor gene is not enough to prevent the development of cancer. Loss of heterozygosity refers to the loss of one specific allele in a diploid cell, aneuploidy refers to an abnormal chromosome number, signal transduction refers to the transfer of a message from the cell surface to the inside of the cell, and clonal evolution refers to the process by which a single cell accumulates mutations and gives rise to a population of genetically diverse cancer cells.

What Is the Rare Situation Called When Only One of the Two