Defects in _____ genes often increase the overall mutation rate of other genes.

Question

Quizplus · Accepted Answer

Defects in DNA repair genes often impair the cell's ability to fix mutations, which can lead to an increase in overall mutation rate. This can eventually contribute to the development of cancer or other genetic disorders. Defects in oncogenes or tumor-suppressor genes can lead to abnormal cell growth and division, but they do not necessarily increase the overall mutation rate of other genes. Proto-oncogenes are normal genes that can become oncogenes if they are mutated, but they also do not directly affect the overall mutation rate.

Defects in _____ Genes Often Increase the Overall Mutation Rate