Which statement is NOT true about base stacking when nucleic acids are in a double-stranded conformation?
A) Stacking interactions occur when two or more bases are positioned with their rings parallel to each other.
B) Stacking interactions are hydrophilic in nature.
C) Stacking involves a combination of van der Waals and dipole-dipole interactions between bases.
D) Base stacking helps to minimize contact of the bases with water.
E) Base stacking interactions are important in stabilizing the three-dimensional structure of nucleic acids.

Question

Quizplus · Accepted Answer

Stacking interactions are actually hydrophobic in nature, as they involve minimizing contact between the hydrophobic bases and the surrounding water molecules.

Which Statement Is NOT True About Base Stacking When Nucleic