Which part of the IgG molecule is NOT involved in binding to an antigen?
A) Fab
B) Fc
C) heavy chain
D) light chain
E) variable domain

Question

Quizplus · Accepted Answer

The Fc portion of the IgG molecule is not involved in directly binding to the antigen. Instead, it interacts with other immune cells and mediates effector functions such as complement activation and antibody-dependent cell-mediated cytotoxicity (ADCC). The Fab portion, which contains the variable domains of both the heavy and light chains, is responsible for binding to the antigen.

Which Part of the IgG Molecule Is NOT Involved in Binding