Which statement about E. coli RNA polymerase is FALSE?
A) Core enzyme selectively binds promoter regions, but cannot initiate synthesis without a sigma factor.
B) RNA polymerase holoenzyme has several subunits.
C) RNA produced by this enzyme will be completely complementary to the DNA template.
D) The enzyme adds nucleotides to the 3' end of the growing RNA chain.
E) The enzyme cannot synthesize RNA in the absence of DNA.

Question

Quizplus · Accepted Answer

The core enzyme of E. coli RNA polymerase requires a sigma factor to recognize and bind to promoter regions; without it, the core enzyme cannot initiate transcription efficiently. Therefore, the statement that the core enzyme selectively binds promoter regions without a sigma factor is false.

Which Statement About E