Which statement about E. coli RNA polymerase (core enzyme) is FALSE?
A) It can start new chains de novo or elongate old ones.
B) It has no catalytic activity unless the sigma factor is bound.
C) It uses nucleoside 5'-triphosphates as substrates.
D) Its activity is blocked by rifampicin.
E) Its RNA product will hybridize with the DNA template.

Question

Quizplus · Accepted Answer

E. coli RNA polymerase (core enzyme) has catalytic activity even without the presence of a sigma factor, although the specificity and efficiency of transcription is greatly enhanced when a sigma factor is present. Therefore, statement B is false.

Which Statement About E