DnaA binds to what sites in the E. coli origin?

Question

Quizplus · Accepted Answer

DnaA binds to both the R (or DNA repeat sequences) and I (or AT-rich sequences) sites in the E. coli origin of replication. The binding of DnaA to these sites is essential for the initiation of DNA replication. The DUE (or DNA unwinding element) site is also present in the origin, but it is not directly bound by DnaA. Rather, the binding of DnaA to the R and I sites induces local DNA unwinding and facilitates the formation of the replication fork at the DUE site.

DnaA Binds to What Sites in the E