Arsenic inhibits the pyruvate dehydrogenase complex by inactivating the dihydrolipoamide component of dihydrolipoyl transacetylase. Which enzyme is also MOST likely to be inhibited by arsenic?
A) GAP dehydrogenase
B) isocitrate dehydrogenase
C) succinyl-CoA synthetase
D) malate dehydrogenase
E) -ketoglutarate dehydrogenase
Correct Answer:
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