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Biology
Study Set
Lehninger Principles of Biochemistry
Quiz 16: The Citric Acid Cycle
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Question 101
Short Answer
The pyruvate dehydrogenase complex catalyzes the oxidative decarboxylation of pyruvate. Two of the steps catalyzed by this complex do not involve any of the carbons of pyruvate. Briefly describe these reaction steps.
Question 102
Essay
Explain in quantitative terms the circumstances under which the following reaction can proceed. L-Malate + NAD
+
→
\rightarrow
→
oxaloacetate + NADH + H
+
Δ
\Delta
Δ
G'° = +29.7 kJ/mol
Question 103
Essay
You are in charge of genetically engineering a new bacterium that will derive all of its ATP from sunlight by photosynthesis. Will you put the enzymes of the citric acid cycle in this organism? Briefly explain why or why not.
Question 104
Short Answer
Germinating plant seeds can convert stored fatty acids into oxaloacetate and a variety of carbohydrates. Animals cannot synthesize significant quantities of oxaloacetate or glucose from fatty acids. What accounts for this difference?