In kidneys, what is the response when the atrial natriuretic factor (ANF) binds to its receptor?
A) increased cAMP concentration in the cytosol
B) activation of protein kinase G (PKG)
C) stimulation of water and sodium excretion
D) both increased cAMP concentration in the cytosol and stimulation of water and sodium excretion
E) both increased cAMP concentration in the cytosol and activation of protein kinase G (PKG)

Question

Quizplus · Accepted Answer

When ANF binds to its receptor in the kidneys, it stimulates the secretion of sodium and water, leading to an increase in urine volume and a decrease in blood volume and blood pressure. This response is known as natriuresis and diuresis. ANF does not directly activate cAMP or PKG in the kidneys.

In Kidneys, What Is the Response When the Atrial Natriuretic