What bone marrow sample is best to determine fat-to-cell ratio and overall cellularity, as well as for searching for malignant cells?

Question

Quizplus · Accepted Answer

A core biopsy provides a larger and more representative sample of the bone marrow, allowing for a more accurate assessment of fat-to-cell ratio and overall cellularity. It also allows for the visualization of the bone marrow architecture and any abnormal infiltrates, which is important for identifying malignant cells. Aspirate smears may not provide a comprehensive snapshot of the bone marrow and may miss abnormal cells or architecture. Peripheral blood and Prussian blue stain are not appropriate for assessing bone marrow cellularity or identifying malignant cells.

What Bone Marrow Sample Is Best to Determine Fat-To-Cell Ratio