A defective gene for adenosine deaminase results in which of the following?
A) a buildup of dATP
B) buildups of dATP, dCTP, dGTP, and dTTP
C) a deficiency of dATP
D) deficiencies of dATP, dCTP, dGTP, and dTTP

Question

Quizplus · Accepted Answer

Defective adenosine deaminase results in a buildup of dATP, which is toxic to lymphocytes, leading to severe combined immunodeficiency (SCID). There is no evidence to suggest that it results in deficiencies of any other nucleotides.

A Defective Gene for Adenosine Deaminase Results in Which of the Following