Which of the following is found in excess in patients with severe combined immune deficiency?
A) dATP
B) dCTP
C) dGTP
D) dTTP

Question

Quizplus · Accepted Answer

In patients with severe combined immune deficiency, there is a deficiency in adenosine deaminase (ADA) enzyme resulting in a buildup of dATP, which inhibits DNA synthesis and lymphocyte proliferation. This can lead to a severe impairment of the immune system. Therefore, choice A (dATP) is found in excess in these patients.

Which of the Following Is Found in Excess in Patients