Many mutations in receptor kinases that lead to cancer allow the receptor to dimerize and become active, even in the absence of signaling molecules. An example is a mutant form of the EGF receptor kinase called Her2/neu. An antibody that prevents dimerization of Her2/neu receptor kinases is being tested for its effectiveness in stopping cancer. At which stage would this drug work?

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The Answer of Many mutations in receptor kinases that lead to cancer allow the receptor to dimerize and become active, even in the absence of signaling molecules. An example is a mutant form of the EGF receptor kinase called Her2/neu. An antibody that prevents dimerization of Her2/neu receptor kinases is being tested for its effectiveness in stopping cancer. At which stage would this drug work?

Many Mutations in Receptor Kinases That Lead to Cancer Allow