Which of the following accurately describes the path traveled by a new protein as it is synthesized and released from the cell?
A)plasma membrane $\rightarrow$ ER $\rightarrow$ vesicle $\rightarrow$ Golgi $\rightarrow$ cytosol $\rightarrow$ external environment
B)cytosol $\rightarrow$ ER $\rightarrow$ Golgi $\rightarrow$ vesicle $\rightarrow$ plasma membrane $\rightarrow$ external environment
C)nuclear envelope $\rightarrow$ ER $\rightarrow$ vesicle $\rightarrow$ Golgi $\rightarrow$ plasma membrane $\rightarrow$ external environment
D)cytosol$\rightarrow$ Golgi $\rightarrow$ ER $\rightarrow$ vesicle $\rightarrow$ plasma membrane $\rightarrow$ external environment
E)nucleus$\rightarrow$ ER $\rightarrow$ Golgi $\rightarrow$ vesicle $\rightarrow$ plasma membrane $\rightarrow$ external environment

Question

Which of the following accurately describes the path traveled by a new protein as it is synthesized and released from the cell?
A)plasma membrane $\rightarrow$ ER $\rightarrow$ vesicle $\rightarrow$  Golgi $\rightarrow$  cytosol $\rightarrow$  external environment
B)cytosol $\rightarrow$  ER $\rightarrow$  Golgi $\rightarrow$  vesicle $\rightarrow$  plasma membrane $\rightarrow$ external environment
C)nuclear envelope $\rightarrow$  ER $\rightarrow$  vesicle $\rightarrow$  Golgi $\rightarrow$ plasma membrane $\rightarrow$  external environment
D)cytosol$\rightarrow$  Golgi $\rightarrow$ ER $\rightarrow$  vesicle $\rightarrow$  plasma membrane $\rightarrow$  external environment
E)nucleus$\rightarrow$  ER $\rightarrow$  Golgi $\rightarrow$  vesicle $\rightarrow$ plasma membrane $\rightarrow$  external environment

Quizplus · Accepted Answer

Proteins are synthesized in the cytosol and then undergo post-translational modifications in the rough endoplasmic reticulum (ER), followed by further modifications in the Golgi apparatus. The modified proteins are then packaged into vesicles and transported to the plasma membrane for secretion into the external environment. Option B accurately depicts this path: cytosol ➞ ER ➞ Golgi ➞ vesicle ➞ plasma membrane ➞ external environment. None of the other options accurately portrays this path.

Which of the Following Accurately Describes the Path Traveled by a New