Kisspeptin is a protein in humans that has an important role in initiating secretion of the releasing factor gonadotropin-releasing hormone (GnRH). Endocrinologists are finding that the protein kisspeptin and its receptor are central to sexual maturation at puberty. Neurons that release kisspeptin carry estrogen receptors. If this is a negative feedback system, high levels of estrogen would be expected to:

Question

Quizplus · Accepted Answer

High levels of estrogen would signal to the neurons that release kisspeptin that there is no need to initiate the secretion of GnRH, and therefore Kisspeptin synthesis would be decreased as a negative feedback mechanism.

Kisspeptin Is a Protein in Humans That Has an Important