Mutations only occur in DNA, and never are observed in RNA.

Name: Mutations only occur in DNA, and never are observed in RNA.
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Mutations can occur in RNA as well as DNA. RNA is an unstable molecule that undergoes more rapid turnover than DNA, so RNA mutations may not persist as long as DNA mutations. However, RNA viruses such as HIV, influenza, and SARS-CoV-2 can accumulate mutations over time that lead to the evolution of new strains or variants of the virus.

Mutations Only Occur in DNA, and Never Are Observed in RNA