Consider Figure 20.25. Imagine that there is a mutation in the gene for the Notch receptor in the progenitor cell. How does mutation affect vulva development?
A)The progenitor cell will become a type 2 cell.
B)The progenitor cell will remain a type 1 cell.
C)The type 2 cell will differentiate into a type 1 cell.
D)The EGF receptor cannot bind its ligand.

Question

Consider Figure 20.25. Imagine that there is a mutation in the gene for the Notch receptor in the progenitor cell. How does mutation affect vulva development? 
A)The progenitor cell will become a type 2 cell. 
B)The progenitor cell will remain a type 1 cell. 
C)The type 2 cell will differentiate into a type 1 cell. 
D)The EGF receptor cannot bind its ligand.

Quizplus · Accepted Answer

The Notch receptor plays a role in promoting the differentiation of the progenitor cell into a type 2 cell, which then induces neighboring cells to adopt a type 1 fate. A mutation in the Notch receptor gene would prevent this differentiation, causing the progenitor cell to remain a type 1 cell, and disrupting normal vulva development. The other answer options are not directly related to the function of the Notch receptor in this pathway.