A cross involving an autosomal gene versus a sex-linked gene would differ in that:

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The phenotype outcomes of females compared to males could be different in a cross involving an autosomal gene versus a sex-linked gene. This is because females have two copies of the autosomal gene, while males have only one copy of the sex-linked gene. Therefore, the expression of the gene may differ between males and females in a cross involving an autosomal gene versus a sex-linked gene.

A Cross Involving an Autosomal Gene Versus a Sex-Linked Gene