A single point mutation in a mitochondrial gene involved in protein synthesis that affects oxidative phosphorylation shows a maternal inheritance pattern that is characteristic of mitochondrial diseases.

Question

Quizplus · Accepted Answer

Mitochondrial diseases are inherited maternally since most of the mitochondria in an individual's cells come from the mother's egg. A single point mutation in a mitochondrial gene involved in protein synthesis can affect oxidative phosphorylation, leading to mitochondrial disease.

A Single Point Mutation in a Mitochondrial Gene Involved in Protein