Why do mutations associated with cancer almost always occur sequentially instead of simultaneously?

Question

Quizplus · Accepted Answer

Each of these statements contributes to understanding why cancer-associated mutations typically occur in a sequential manner rather than simultaneously. Mutations are rare events, making simultaneous mutations in the same cell highly unlikely (A). Each mutation can confer a growth advantage, increasing the population of cells that can acquire further mutations (B and C).

Why Do Mutations Associated with Cancer Almost Always Occur Sequentially