Sickle-cell anemia results from what type of mutation?

Name: Sickle-cell anemia results from what type of mutation?
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Sickle-cell anemia is caused by a missense mutation, where a single nucleotide change results in the substitution of one amino acid for another in the hemoglobin protein. This specific mutation changes the sixth amino acid from glutamic acid to valine, leading to the characteristic sickle shape of red blood cells in affected individuals.

Sickle-Cell Anemia Results from What Type of Mutation