The first line of treatment for youth with moderate or severe depression is individual CBT, IPT, or short-term family therapy. According to the guidelines, antidepressant medication

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The guidelines recommend that antidepressant medication should only be offered in combination with a psychological treatment for youth with moderate or severe depression. It is not the first line of treatment and should be used as a last resort if non-pharmacological treatments have not been effective or if the youth is at significant risk of harm to themselves or others. Antidepressant medication should not be the only treatment option offered.

The First Line of Treatment for Youth with Moderate or Severe