Mice that are homozygous mutant for Small eyes/Pax6 completely lack eyes. If you were to express the fly Eyeless gene in the eye primordia of a mouse embryo during development, you would expect to see mice with:
A) no eyes.
B) mouse eyes in the appropriate location.
C) fly-like compound eyes in the appropriate location.
D) extra mouse eyes growing in other parts of their bodies.
E) extra fly-like compound eyes growing in other parts of their bodies.

Question

Quizplus · Accepted Answer

Judging from analogous experiments in flies, Pax6 and Eyeless are so highly conserved that they can still interact with other protein players and regulate the expression of many downstream genes to promote the development of species-appropriate eyes. If only expressed in the eye primordia, Eyeless should only produce mouse eyes in their usual location.

Mice That Are Homozygous Mutant for Small Eyes/Pax6 Completely Lack