What do you predict would happen if the activity of hypocretin neurons in the hypothalamus were genetically silenced?
A) The animal would spend more time asleep.
B) The animal would spend more time awake.
C) The animal would have an increased probability of making a transition from REM sleep to wake.
D) The animal would not be able to sleep at all.

Question

Quizplus · Accepted Answer

This is the opposite experiment as that shown in Figure in which activation of hypocretin-expressing cells with ChR2 increased the probability that animals wake up from sleep. All other answers beside a. suggest the animal will spend more time awake, which are not correct.

What Do You Predict Would Happen If the Activity of Hypocretin