Question 1

Match each item with the correct statement below.
-All may be used to treat inflammation.

Accepted Answer

NSAIDs, corticosteroids, and COX-2 inhibitors are commonly used to treat inflammation.

Question 2

Used only by medical personnel during procedures; paralyze muscles.

Accepted Answer

NMBAs, or neuromuscular blocking agents, are drugs used by medical personnel during procedures to paralyze muscles temporarily.

Question 3

Potentiation of skeletal muscle relaxants may occur when taken with which of the following?

Accepted Answer

Alcohol, analgesics, psychotropic medications, and antihistamines can potentiate the effects of skeletal muscle relaxants by enhancing central nervous system depression or through other mechanisms, leading to increased muscle relaxation and potential side effects.

Question 4

Match each item with the correct statement below.
-Only skeletal muscle relaxant with direct effect on muscle; for MS, cerebral palsy not injury.

Accepted Answer

Dantrolene is the only skeletal muscle relaxant that works directly on the muscle, and it is used for conditions like multiple sclerosis (MS) and cerebral palsy, not for muscle injury.

Question 5

Match each item with the correct statement below.
-Osteoporosis therapy

Accepted Answer

Bisphosphonates are a class of drugs that are commonly used in the treatment of osteoporosis to strengthen bones and prevent fractures.

Question 6

Which of the following produces estrogen agonist activity that results in increased bone mineral density to reduce fracture risk without promoting breast or endometrial cancer?

Accepted Answer

Selective estrogen-receptor modifiers (SERMs) are designed to produce estrogen-like effects on bone, increasing bone mineral density and reducing fracture risk, without the estrogenic stimulation of breast and endometrial tissue that can increase cancer risk.

Question 7

Used for postmenopausal osteoporosis prevention.

Accepted Answer

Hormone replacement therapy (HRT) is used for the prevention of postmenopausal osteoporosis. It helps to compensate for the decrease in estrogen levels after menopause, which can lead to a decrease in bone density.

Question 8

Match each item with the correct statement below.
-GI bleeding

Accepted Answer

The answer of Match each item with the correct statement...

Question 9

Neuromuscular blocking agents, or NMBAs, are potentially very dangerous due to the risk of respiratory arrest, which is caused by _________.

Accepted Answer

Neuromuscular blocking agents can cause paralysis of the diaphragm, which is a critical muscle for breathing, leading to respiratory arrest.

Question 10

Oldest type of these are salicylates (aspirin); associated with GI bleeding and ulcers

Accepted Answer

NSAIDs, or nonsteroidal anti-inflammatory drugs, include aspirin among their oldest types. They are known to be associated with gastrointestinal issues such as bleeding and ulcers.

Question 11

Used for short period of time in acute injuries for pain and spasm.

Accepted Answer

Skeletal muscle relaxants are used for a short period of time to relieve pain and muscle spasms associated with acute injuries.

Question 12

The beneficial effects of NSAIDs are brought about by which action?

Accepted Answer

NSAIDs work by inhibiting the enzyme cyclooxygenase (COX), which is responsible for the synthesis of prostaglandins, compounds that mediate inflammation, pain, and fever.

Question 13

Side effects with muscle relaxants include ________.

Accepted Answer

Muscle relaxants commonly cause side effects such as drowsiness, weakness, tremor, slurred speech, blurred vision, and urinary problems.

Question 14

Which of the following are nonhormonal agents that act directly to inhibit bone reabsorption?

Accepted Answer

Bisphosphonates are nonhormonal agents that act directly to inhibit bone reabsorption.

Question 15

The side effects of COX-2 agents are _________.

Accepted Answer

COX-2 inhibitors are known to potentially increase the risk of hypertension, atherosclerosis, and clotting due to their selective inhibition of the cyclooxygenase-2 enzyme, which plays a role in inflammation and pain but also has protective effects in the cardiovascular system.

Question 16

Which of the following instructions would be MOST appropriate for a patient receiving osteoporosis therapies?

Accepted Answer

Caffeine can interfere with calcium absorption, which is important for bone health in patients with osteoporosis.

Question 17

Which response after patient education for NSAIDs and muscle relaxants indicates the need for follow up?

Accepted Answer

Bleeding of the gums is not a typical side effect of NSAIDs or muscle relaxants and indicates a misunderstanding or a potential adverse reaction that needs follow-up.

Question 18

NSAID does not inhibit COX-1; does not pose bleeding risks but may increase cardiac risk.

Accepted Answer

COX-2 inhibitors are designed to selectively inhibit the COX-2 enzyme, which is primarily involved in inflammation and pain, without inhibiting COX-1, which helps protect the stomach lining and maintain platelet function. Therefore, they do not pose the same bleeding risks as traditional NSAIDs that inhibit both COX-1 and COX-2, but they may increase the risk of cardiac events.

Question 19

Match each item with the correct statement below.
-Only skeletal muscle relaxant currently a schedule drug

Accepted Answer

Carisoprodol (Soma) is the only skeletal muscle relaxant that is classified as a controlled substance due to its potential for abuse and dependence.

Question 20

Which of the following medications may prevent the accelerated phase of bone loss within the first 5 years following the onset of menopause?

Accepted Answer

Estrogen replacement therapy is known to help prevent bone loss in postmenopausal women by compensating for the decreased estrogen levels that contribute to accelerated bone loss.

Quiz 21: Musculoskeletal and Anti-Inflammatory Drugs

Match each item with the correct statement below. -All may be used to treat inflammation.