A 43-year-old woman is being evaluated for exertional dyspnea. She has a history of right leg deep vein thrombosis that was diagnosed 18 years ago during the postpartum period of her first pregnancy. Her other medical problems include hypertension, hyperlipidemia, type 2 diabetes, and asymptomatic gall stones. She works in a local textile factory and has 20 pack-year smoking history.
Her blood pressure is 150/90 mm Hg and pulse is 76/min. Her BMI is 36 kg/m2. Examination shows a plethoric appearance, mild facial hirsutism, and abdominal skin stretch marks. Lungs are clear to auscultation. There is no leg swelling. Arterial blood gas findings demonstrate a pH of 7.35, pCO2 of 45 mm Hg, and pO2 of 65 mm Hg.
Pulmonary function tests are shown below.
Which of the following is the most likely cause of her dyspnea?
A) Chronic obstructive pulmonary disease
B) Neuromuscular disease
C) Obesity
D) Occupational lung disease
E) Thromboembolic pulmonary hypertension
Correct Answer:
Verified
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