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Women Are Cautioned Against Having Children Later in Life Because

Question 42

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Women are cautioned against having children later in life because the incidence of Down syndrome (trisomy 21) increases rapidly with age.What is the best explanation for this phenomenon?


A) Somatic mutations accumulate as a woman gets older,leading to changes in the uterine environment that cause down syndrome.
B) Germ line mutations accumulate as a woman ages,so a larger percentage of her eggs have mutations.
C) Germ line mutations accumulate as a woman gets older,leading to changes in the uterine environment that cause down syndrome.
D) Somatic mutations accumulate as a woman ages,so a larger percentage of her eggs have mutations.
E) Somatic mutations accumulate as a woman ages,so the developing embryo is more likely to acquire mutations that lead to down syndromE.

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