A 23-year-old woman comes to the physician due to acute nausea and vomiting. She recently returned from a vacation to Mexico and started to feel "queasy" on the last day of her trip. The patient then developed nausea with frequent vomiting and intermittent bouts of watery diarrhea. She has no visible blood in her stools. Her temperature is 36.8 C (98 F), blood pressure is 118/70 mm Hg, pulse is 86/min, and respirations are 12/min. Abdominal examination shows mild tenderness and increased bowel sounds. Improvement of this patient's vomiting would best be achieved by a medication targeting which of the following receptors?

Question

A 23-year-old woman comes to the physician due to acute nausea and vomiting.  She recently returned from a vacation to Mexico and started to feel "queasy" on the last day of her trip.  The patient then developed nausea with frequent vomiting and intermittent bouts of watery diarrhea.  She has no visible blood in her stools.  Her temperature is 36.8 C (98 F), blood pressure is 118/70 mm Hg, pulse is 86/min, and respirations are 12/min.  Abdominal examination shows mild tenderness and increased bowel sounds.  Improvement of this patient's vomiting would best be achieved by a medication targeting which of the following receptors?

Quizplus · Accepted Answer

Eductional Objective: 5-HT₃ receptor antagonists are useful for the treatment of visceral nausea due to gastrointestinal insults, such as gastroenteritis, chemotherapy, and general anesthesia. Antihistamines and anticholinergics are recommended for vestibular nausea. Dopamine antagonists are useful for nausea associated with migraine.

A 23-Year-Old Woman Comes to the Physician Due to Acute