A 60-year-old woman with a seizure disorder is brought to the emergency department because of progressive lethargy over the past week. she has also a headache and nausea for several days. Her vital signs are within normal limits. She appears lethargic and is only oriented to person. Oral mucosa is moist. There is no jugular venous distention. A basic metabolic panel shows a serum sodium concentration of 117 mEq/L but is otherwise normal. Serum osmolality is low and urine osmolality is high X-ray of the chest shows no abnormalities Which of the following medications is the most likely cause of this patient's condition?

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Quizplus · Accepted Answer

Eductional Objective: Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most common cause of euvolemic hypotonic hyponatremia. hyperosmolar urine Carbamazepine can cause SIADH by increasing antidiuretic hormone (ADH) secretion and renal sensitivity to ADH.

A 60-Year-Old Woman with a Seizure Disorder Is Brought to the Emergency