A 70-year-old man is being evaluated due to hearing impairment. He states that he doesn't hear sounds very well and needs be closer to hear his wife or listen to TV. He has a history of hypertension, diabetes mellitus and heart failure, last week, he was admitted to the hospital because of heart failure exacerbation and a new adjustment to his medication was done. He says I was feeling well before admission. Examination shows moderate bilateral sensorineural hearing loss. Which of the following medications most likely contributed to this patient's hearing impairment?

Question

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Eductional Objective: 
Ototoxicity secondary to loop diuretics usually occurs with higher dosages, pre-existing chronic renal disease, rapid intravenous administration, or when used in combination with other ototoxic agents (aminoglycosides, salicylates, and cisplatin). Hearing impairment is usually reversible but may be permanent in some cases.

A 70-Year-Old Man Is Being Evaluated Due to Hearing Impairment