A 25-Year-Old Woman Presented to the Office Due to Fatigue

A 25-year-old woman presented to the office due to fatigue. The patient has been sleeping poorly, with difficulty getting out of bed for the last month. She complains of less productivity at work. She has been feeling out of the mood, with a loss of interest in most of her activities. Her appetite has decreased over the same period. The patient has no significant medical or psychiatric history. Laboratory studies including thyroid studies and B12 levels are normal. Physical examination is unremarkable. A mental examination shows depressed mood and affect. No delusions are elicited. She has no suicidal thoughts. The drug of choice for this patient, has which of the following mechanisms of action?

A) Antagonism of dopamine D2 receptors
B) Antagonism of serotonin 5-HT2 receptors
C) Inhibition of sodium channels
D) Inhibition of the serotonin transporter
E) Inhibition of monoamine oxidase
F) Potentiation of the effects of endogenous GABA