Which one of the following statements about dendritic cells is true?
A) Immature dendritic cells are ubiquitously present in skin and mucosal tissues.
B) Dendritic cell maturation occurs after migration to lymph nodes in response to signals derived from activated T cells.
C) Class II MHC and T cell costimulators are highly expressed on immature dendritic cells and are down-regulated during maturation.
D) Dendritic cells that enter lymph nodes through draining lymphatics migrate to the B cell-rich follicles in response to chemokines.
E) The principal function of mature dendritic cells is antigen capture.
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