It is of particular importance to monitor drug levels in patients for drugs that have a ______ therapeutic index.A therapeutic index of 2.0 is associated with a high likelihood of the patient experiencing ______.

Question

Quizplus · Accepted Answer

The ratio of the minimum dose associated with toxicity divided by the minimum dose that produces the desired therapeutic response in a patient population is known as the therapeutic index.It is particularly desirable to monitor drug concentrations for drugs that have a narrow range between these two doses (i.e., a low therapeutic index).When the therapeutic index is 2.0 or less, the drug may be difficult to use in patients without significant toxicity being encountered.

It Is of Particular Importance to Monitor Drug Levels in Patients