The Inflammatory Activity of Adipose Tissue, Particularly Visceral Fat, Is

The inflammatory activity of adipose tissue, particularly visceral fat, is enhanced in obese individuals. This effect of obesity is, in part, due to adipose tissue resistance to the actions of insulin. Insulin resistance in adipose tissue is reflected by a reduction in production of which of the following adipokines?

A) adiponectin
B) C-reactive protein, CRP
C) monocyte chemotactic protein-1, MCP-1
D) vascular cell adhesion molecule-1, VCAM-1
E) vascular endothelial cell growth factor, VEGF