You Are Studying the Responses of Fat Cells in Culture

You are studying the responses of fat cells in culture to the addition of various pharmacologic compounds. You find that addition of a β-adrenergic agonist does not result in the expected change in mitochondrial proton gradients. This would indicate that there was most likely a defect in the function of which of the following?

A) adiponectin
B) adipose triglyceride lipase
C) fatty acid synthase
D) leptin
E) UCP1