A 55 year old woman fell while touring London.She sustained a fracture of her humerus,just below the head of the humerus.The fracture was surgically repaired and sample of bone tissue was taken and sent to pathology.The sample is shown in the accompanying image with normal bone on the left for comparison.Both sections are undecalcified,and are stained with Goldner's trichrome,which stains uncalcified osteoid pink,and calcified matrix green.Which one of the following diagnoses is most likely correct?
A)Osteogenic sarcoma
B)Osteoporosis
C)Osteomalacia
D)Osteomyelitis
E)Paget's disease of bone

Question

A 55 year old woman fell while touring London.She sustained a fracture of her humerus,just below the head of the humerus.The fracture was surgically repaired and sample of bone tissue was taken and sent to pathology.The sample is shown in the accompanying image with normal bone on the left for comparison.Both sections are undecalcified,and are stained with Goldner's trichrome,which stains uncalcified osteoid pink,and calcified matrix green.Which one of the following diagnoses is most likely correct? 
A)Osteogenic sarcoma 
B)Osteoporosis 
C)Osteomalacia 
D)Osteomyelitis 
E)Paget's disease of bone

Quizplus · Accepted Answer

The woman is likely post-menopausal,so you would expect a diagnosis of osteoporosis.The histology confirms this impression,with a much thinner bone spicule,when compared to the normal sample on the left.

A 55 Year Old Woman Fell While Touring London