The inhibition of the synthesis of DNA by methotrexate results from direct inhibition of
A) a reaction in the pathway of purine biosynthesis.
B) thymidylate synthase.
C) the reduction of ribonucleotides to deoxyribonucleotides.
D) synthesis of S-adenosylmethionine.
E) the reduction of dihydrofolate to tetrahydrofolate.
Correct Answer:
Verified
Q38: Hypoxanthine-guanine phosphoribosyl transferase (HGPRTase)
A) can catalyze the
Q40: In pyrimidine biosynthesis, the carbon atoms in
Q41: Provides the number 3 nitrogen of the
Q41: What is contained within a nucleoside?
A) a
Q42: Sources of the single carbons carried by
Q44: Which of the following is involved in
Q45: The action of methotrexate in inhibiting cell
Q46: The committed step in purine biosynthesis is
A)
Q47: All of the following enzymes play a
Q48: M12321Absence or inhibition of the enzyme hypoxanthine-guanine
Unlock this Answer For Free Now!
View this answer and more for free by performing one of the following actions
Scan the QR code to install the App and get 2 free unlocks
Unlock quizzes for free by uploading documents